20xx年标书(编辑修改稿)

20xx年标书(编辑修改稿)内容摘要：

要参考文献 （ 1） Burns A, Zaudig M. Mild cognitive impairment in older people. Lancet, 2020。 360:19631965 （ 2） Albert MS. Cognitive and neurobiologic markers of early Alzheimer disease. Proc Natl Acad Sci USA, 1996, 93:1354713551 （ 3） Mitchell A, Brindle N. CSF phosphorylated tau— does it constitute an accurate biological test for Alzheimer’s disease? International Journal of Geriatric Psychiatry, 2020, 18:407411 （ 4） Nitsch RM, Rcacck GW, Deng M,et al. Cerchrospinal fluid levels of amyloid223。 protein in Alzheimer’s disease。 Inverse correlation with severity of demtia and effect of apolipo protein E genotype, Neurol,1995,87:512518 （ 5） Encinas M, De Juan R, Marcos A, et al. Regional cerebral blood flow assessed with 99mTcECD SPET as a marker of progression of mild cognitive impairment to Alzheimer’s disease. Euro J Nucl Mol Imaging, 2020, 30:14731480 （ 6） Este180。 vezGonza180。 lez A, Kulisevsky J, Boltes A, et al. Rey verbal learning test is a useful tool for differential diagnosis in the preclinical phase of Alzheimer’s disease: parison with mild cognitive impairment and normal aging. Int J Geriatr Psychiatry 2020。 18: 1021–1028 （ 7） Demattos RB, Bales KR, Cummins DJ, et al. Brain to plasma amyloid223。 efflux: A measure of brain amyloid burden in a mouse model of Alzheimer’s disease. Science, 2020, 295:22642267 （ 8） Kung MP, Catherine H, Zhuang ZP, et al. IMPY: An improved thioflavinT derivative for in vivo labeling of 223。 –amyloid plaque. Brain Reseach, 2020, 956:202210 （ 9） Skovronsky DM, Bin Z, Kung MP, et al. In vivo detection of amyloid plaques in a mouse model of Alzheimer’s disease. Neurobiology, 2020, 97:76097614 （ 10） 王力，程灶火，李欢欢 . Alzheimer 病人记忆损害特征的研究。 心理科学，2020 年第 4 期 （ 11） Kemppainen N, Laine M, Laakso MP, et al. Hippocampal dopamine D2 receptors correlate with memory functions in Alzheimer39。 s disease. Eur J Neurosci. 2020 Jul。 18(1):14954. （ 12） Mega MS, Chu T, Mazziotta JC,et al. Mapping biochemistry to metabolism:。