高龄老年人冠心病合并肺栓塞一例(编辑修改稿)内容摘要：
• 下肢血管彩超：双下肢动脉粥样硬化，右侧小腿肌间静脉血栓形成，范围 ，深静脉未见明显血栓 • CTPA：双肺动脉主干及分支未见明显异常 下一步治疗措施。 VTE? • 阿司匹林加量至 100mg+氯吡格雷 dual antiplatelet therapy (DAPT) • 阿司匹林或氯吡格雷 +华法林 oral anticoagulation (OAC) • 阿司匹林 +氯吡格雷 +华法林 triple oral antithrombotic therapy (TOAT) • 其他 TOAT vs. DAPT • 临床证据较少，多来自观察性研究 • TOAT似乎优于 DAPT 1. In a study of 426 patients with atrial fibrillation (AF) undergoing percutaneous coronary intervention (PCI), DAPT was prescribed in 41 and TOAT in 50 percent . Nonanticoagulation was associated with increased mortality (28 versus 18 percent。 hazard ratio [HR] , 95% CI ). 2. In a propensity matching study of 604 registry patients with AF undergoing PCI, OAC prescription at discharge was associated with a lower rate of major adverse cardiovascular events (HR , 95% CI ) and allcause mortality (, 95% CI ) . 3. In a retro。阅读剩余 0%
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