analysisofpathogenesisofsymptomaticvenous

analysisofpathogenesisofsymptomaticvenous内容摘要：

gnificant difference was observed in age (P＞ ). Materials Gene expression analysis  Whole Human Genome 60mer Oligo Microarrays (G4112A, Agilent Technologies), representing the entire human genome (44290 spots) were used to investigate RNA expression patterns.  41675 genes or transcripts。 314 negative control spots, 1942 positive control spots, 359 blank spots； more than 70% of genes have definite functions. Patients and materials Patients and materials Statistical analysis Analysis of differentially expressed genes  Primary data of genechip collected by Agilent Feature extraction software were standardized by robust multichip method.  The standardized gene intensity data of PE group and control group were pared by t’ test.  Differentially expressed genes were screened, and P was considered statistically significant. Statistical analysis Gene Ontology analysis  Analysis of molecular mechanisms Enrichments of differently expressed genes were achieved based on their relative ratios in Gene ontology classification. The higher the enrichments, the more they contribute to gene differential expression Results(1)－ adhesion molecules mRNA expression of genes related with adhesion molecules Normalized gene signal values PTE group Control group Results(2)－ coagulation factors Normalized gene signal values PTE group Control group mRNA expression of genes related with coagulation factors Results(3)－ anticoagulant proteins Normalized gene signal values PTE group Control group mRNA expression of genes related with。